WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:
Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName #Gene EntrezGene Statistics
Metabolic pathways 185 349565 317749 4712 7381 5435 29796 56922 2746 1339 522 1352 587 2806 517 7385 4714 51102 3373 8801 4715 4731 54995 4700 4705 1738 4720 5160 35 4717 124454 8813 2271 25902 51809 1743 5162 80142 515 2531 23530 226 211 4722 9377 7388 4702 1340 1158 1329 1962 4726 3028 1327 4697 54344 81579 1345 122622 374291 4724 10476 2027 4708 1537 1152 10975 27034 51606 51805 64087 516 8803 84284 5438 7923 64802 669 5095 3421 6342 1635 5315 10901 4716 10063 6390 2235 51601 2590 55750 283871 5439 509 283208 27349 4190 498 2821 1717 84532 37 4718 4698 4351 8802 4191 8382 64131 7389 4711 1160 3418 521 4706 253558 6389 4709 80146 7386 55229 5336 1431 2805 326625 155066 84693 4704 1350 2597 5441 27089 48 27235 514 2585 4707 8050 513 6392 50 9380 51181 2539 4694 4713 7167 22934 549 4719 6391 10873 11019 506 30 51004 10682 128 4723 4695 4710 3290 51227 4728 1349 56953 4696 3945 55163 10632 5096 217 1892 7384 9551 3033 518 51 5730 1351 2720 4725 3420 132 112483 539 C=1130;O=185;E=29.45;R=6.28;rawP=2.08e-92;adjP=3.06e-90
Oxidative phosphorylation 79 4718 4698 4712 7381 29796 1346 4711 4706 521 1339 54539 522 1352 6389 4709 7386 517 7385 4714 4715 4731 4700 4705 4720 155066 4704 4717 1350 27089 514 4707 513 515 6392 4694 27068 4722 9377 7388 4713 4702 1340 1329 4719 6391 4726 4697 1327 506 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 10975 1537 1349 51606 55967 4696 516 10632 7384 9551 4716 6390 10063 518 509 9167 1351 4725 498 539 C=132;O=79;E=3.44;R=22.96;rawP=3.84e-90;adjP=2.82e-88
Parkinson's disease 77 4718 4698 4712 7381 29796 1346 4711 4706 1339 54539 522 6389 11315 4709 7386 517 7385 4714 7419 4715 4731 4700 4705 4720 4704 4717 1350 27089 7417 514 4707 7416 513 515 6392 291 4694 9377 4722 7388 4713 4702 1340 1329 4719 6391 4726 4697 54205 1327 506 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 1537 10975 1349 55967 4696 516 7384 4716 6390 518 509 9167 1351 4725 498 539 C=130;O=77;E=3.39;R=22.73;rawP=2.31e-87;adjP=1.13e-85
Huntington's disease 83 4718 4698 4712 7381 5435 29796 1346 4711 4706 1339 25942 54539 522 6389 4709 7386 517 7385 4714 7419 4715 4731 4700 4705 4720 10126 4704 6647 4717 1350 5441 27089 7417 514 4707 7416 513 515 6392 291 4694 9377 4722 7388 4713 4702 1340 1329 4719 6391 4726 4697 54205 1327 506 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 1537 10975 1349 55967 4696 516 5438 7384 4716 6390 5439 518 509 9167 1351 498 4725 539 C=183;O=83;E=4.77;R=17.40;rawP=4.80e-81;adjP=1.76e-79
Alzheimer's disease 78 4718 4698 4712 7381 29796 1346 4711 4706 1339 54539 522 6389 4709 7386 517 7385 4714 4715 4731 4700 4705 4720 8883 4704 4717 1350 2597 27089 4035 514 4707 513 515 6392 4694 4722 9377 7388 4713 4702 1340 1329 4719 6391 23621 4726 3028 4697 54205 1327 506 1345 374291 1347 4724 4723 4695 4710 10476 4708 348 4728 1537 10975 1349 55967 4696 516 7384 4716 6390 518 509 9167 1351 4725 498 539 C=167;O=78;E=4.35;R=17.92;rawP=1.81e-77;adjP=5.32e-76
Citrate cycle (TCA cycle) 20 8803 5160 8802 6391 4191 3421 48 2271 3418 1743 5162 6389 6392 6390 50 1431 8801 4190 3420 1738 C=30;O=20;E=0.78;R=25.58;rawP=4.16e-25;adjP=1.02e-23
Cardiac muscle contraction 26 7134 1329 1350 7137 7169 7381 27089 29796 1346 1327 7384 1339 1345 55799 1347 7386 9167 1351 7385 9377 7388 1537 10975 1349 1340 4634 C=77;O=26;E=2.01;R=12.96;rawP=3.23e-22;adjP=6.78e-21
Valine, leucine and isoleucine degradation 17 84693 35 5096 549 217 1962 5095 1892 3028 56922 30 587 5019 3033 27034 1738 64087 C=44;O=17;E=1.15;R=14.82;rawP=3.71e-16;adjP=6.82e-15
Peroxisome 19 5824 6647 1962 8528 6342 5827 3418 30 1891 10901 390916 8799 373156 5191 1384 51 25824 8443 10455 C=79;O=19;E=2.06;R=9.23;rawP=1.39e-13;adjP=2.27e-12
Pyruvate metabolism 14 5160 9380 217 4191 10873 2739 98 4190 5315 1738 84532 197257 5162 3945 C=40;O=14;E=1.04;R=13.43;rawP=7.61e-13;adjP=1.12e-11


WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).